If young women take certain simple steps when they are adolescents, they may reduce risk of breast cancer later in life. A research suggests that puberty could be a crucial time for development of breast cancer. Regular exercise is believed to delay the beginning of a girl's first menstrual period. That is when the body creates hormones that stimulate the majority of breast cancers. According to a study, just 4 hours of weekly exercise can postpone hormone surges for up to 12 months. Four hours a week is not a large amount of activity for a girl. She can play dodge ball, play on the playground or ride her bike. Because exercise can lower hormone activity, it can reduce risk of breast cancer, even after a girl starts having periods. One more way is cutting back on fat. Girl who cut her fat intake by only 6 percent lowered her estrogen and progesterone levels by at least 30 percent, according to a study. These theories are not really well tested and need more research. Breast cancer is the most common cancer in women, other than skin cancer. In the United States approximately 183,000 new cases are diagnosed and about 41,000 women die each year from cancer originating in the breast.
Chemotherapy is a word that strikes fear into most of our hearts. We've seen the movies and heard such horrible stories about undergoing this difficult treatment for a disease that could very well kill us. I underwent chemo for breast cancer and know that, in some cases, the cancer isn't hard … it isn't painful … it doesn't make us sick. That's the case for most of us who have breast cancer, but don't have distant metastases. But then, they say we need to do chemo and we know we'll feel that. Although chemo drugs haven't changed that much, and they're still terribly hard on our bodies, the management drugs have changed a lot. Chemotherapy, for many of us, isn't the show-stopper we thought it would be. Of course, each of us is different and the chemo drugs affect each of us in different ways, but, for the most part, chemo is definitely doable. My breast cancer was Stage IIIa, with a 5.8 cm tumor, 8 of 10 lymph nodes positive, and I was only 39 years old. That bought me a ticket for the chemo ride. And I was scared out of my wits. But, I found an online breast cancer support group, at WebMD, and those women told me everything to expect and more. I went through four rounds of adriamycin and cytoxan. Both of them are some pretty stout breast cancer chemo drugs. After that, I did a controversial treatment that involved extremely high doses of cytoxan, taxol, and cisplatin, so I learned quite a bit about surviving chemotherapy. First of all, I would highly recommend getting a port. This is a line that goes into a vein in your chest, the entrance to which sits just under your skin, right below your collarbone. It requires a quick surgery to put it in but, if you're having a mastectomy for your breast cancer, you can get the chemo port put in at the same time. If you choose not to do that, you'll have to get your chemo treatments through your veins and chemo is really hard on your veins. This means that you will, most likely, have to endure multiple attempts for them to find a vein, as time goes by. With the port, it's already in a vein, so all they have to do is stick the needle into the port to access it. If you find this uncomfortable, there is a cream they can give you called Emla cream. One of the first things I learned was to tell them the moment I was uncomfortable. It's all fixable. You'll put the Emla cream on a bit before you have to have your port accessed and it'll numb your skin. Most breast cancer chemotherapy drugs will cause your hair to fall out. This is because chemo kills the rapidly dividing cells in your body. Your mucous areas and hair follicles are affected for this reason. That's why you may have nausea or develop mouth or throat sores. Again, all this sounds scary, but is totally manageable. Since you will probably be losing your hair, which can be quite traumatic, I would advise going wig or hat shopping before you even get your first chemo. Take a girlfriend with you and be adventurous. Try on different styles, and even colors. If you've always wanted to be a blonde, now's your chance! Make a day of it and have fun with it. Goodness knows, you have to look for that silver lining every chance you get. Also, make sure to have your nausea med prescription filled before you go so you'll have it waiting for you if you need it at home. You may be pretty tired, afterward, so don't wait till then to get those meds. On your first chemo day, they will probably give you some steroids, intravenously or through your port, to help with the nausea. This may make you hungry; it sure did for me! But, I would recommend you don't eat your favorite food on chemo day. Chemo is manageable, but after you're all done, you may find that you have associations. For example, I used to love the cucumber melon fragrance when I was going through chemo. I had cucumber melon everything! But, to this day, the smell of cucumber melon makes my stomach do a little somersault because it reminds me of such an unpleasant time in my life. The same can happen with food. I still can't look a chicken burrito in the eye! But, I'm sure glad I didn't eat a taco because I would've hated for that to be ruined for me! Many breast cancer chemo drugs are hard on your bladder, so be sure to drink, drink, drink. If you don't feel like drinking water, then broth, jello, or even popsicles will help. Since you've gotten your nausea meds all filled in advance, be sure to take them as prescribed, whether you think you need them or not. Chemo nausea isn't just any kind of nausea and it's much easier to stay ahead of it than to try to fix it once it occurs. If you do happen to get nauseated, and I can't stress this enough, call your doctor!!! There are many, many nausea meds and you do not have to feel sick just because you're doing chemo. Once they find the right drug for you, it will be so much easier. So, do not suffer this in silence! The same applies for if you get sores in your mouth or throat. You will be tired from this treatment. Most of us get more tired as the treatments progress because they make our white blood cell counts drop really low. Because of this, it's a good idea to keep some Purell, or something similar, with you all the time for use when you've had to touch, for example, public restroom door handles. Your risk of infection will be much higher during this time. If you lose your hair, it will typically happen in 10-14 days after your first chemo treatment. If you have long hair, you might want to cut it short in preparation. I know I felt so out of control of everything, during that time. When your hair comes out, it lets go quickly and in large clumps, getting all over your pillow and clogging your drain. For many women, that is more traumatic than even losing a breast. So, I figured that was the one thing I could control about this whole breast cancer thing … when my hair came out. I cut it really short, beforehand and, when it started to let go, I had my husband get the clippers and shave my head. My daughter helped and we did a little Mohawk and stripe action first! That was my way of shaking my fist at this cancer … it might take my breasts, and it might take my hair for a while, but I beat it to the punch! It was my way of saying, "You cannot take my spirit!" You can do the same thing. Your breast cancer does not define you. It is but a speed bump in the course of your life. Strap on your gloves and step into the ring. This chemo is your biggest punch. Your spirit is your own and that breast cancer can't touch it!
Your team of doctors will make treatment recommendations based on the stage of your cancer. Your standard treatment options may include surgery, chemotherapy, radiation, and hormone therapy. If you have been diagnosed with DCIS or LCIS, your stage is the lowest and the road you will travel will be easier. For DCIS, your options may include breast-conserving surgery or mastectomy with or without radiation and hormone therapy. LCIS treatments options are a bit different. They include observation to determine changes, hormone therapy to prevent cancer from developing, or bilateral prophylactic (preventive) mastectomies. Things get more complicated when your cancer spreads beyond the ducts or lobes/lobules. Once your cancer has been staged, you can visit cancer. gov to determine your treatment options. They will typically include: surgery, chemotherapy, radiation, and/or hormone therapy. For IBC, treatment options are similar to the other types of breast cancer, but they will always include chemotherapy because of its aggressiveness. • Surgery: Breast surgery can be either a lumpectomy, where the tumor is removed, or a partial or modified radical mastectomy. With a lumpectomy, it is typically followed by radiation. This way, you get to keep your breast and studies have shown no difference in survival rates between lumpectomy/radiation and mastectomy. Note: Not too long ago, they used to perform radical mastectomies where the breast, all the lymph nodes, and the underlying muscle were cut away. Thankfully, medicine has discovered that's not necessary. Now, a partial or modified radical mastectomy is performed, where either part of the breast tissue, or the entire breast, and possibly a portion of the lymph nodes, are removed. On the whole, a mastectomy isn't too bad a surgery, although everyone is different. I found both of mine to be quite easy, but you will wake up with drain tubes, which you’ll typically have for at least a week. • Chemotherapy: Chemotherapy is defined by Wikipedia as “the use of chemical substances to treat disease. In its modern-day use, it refers primarily to cytotoxic drugs used to treat cancer.” This can be a frightening prospect for anyone. We've all heard horror stories about how very debilitating chemotherapy can be. However, much progress has been made in the management of chemo's side effects, to the point that, once you have the right management tools, you can continue to enjoy the activities you typically do. Chemo is a means of treating your cancer systemically and is typically recommended for those whose tumor is larger than a certain size and/or the cancer has spread to your lymph nodes. The thinking is that if your cancer has had the opportunity to access the rest of your body, your treatment should be systemic as well. • Radiation: Radiation therapy is typically a localized treatment option, where rapidly dividing cells are damaged. Cancer cells are very rapid dividers, so radiation is an effective option. Typically, radiation therapy is given for about six weeks, five days a week. It's very much like lying still for an x-ray, only instead of lasting a second or two, it lasts a couple of minutes. It can cause fatigue, toward the end and slightly after, and can cause a sunburn effect on your skin. • Hormone Therapy: Many breast cancers are hormone-dependent. In these cancers, there are receptors on the tumor that can be filled with estrogen. The thinking is that when estrogen fills these receptors, it causes the tumor to grow. This is called estrogen-receptor positive (ER). These cancers respond well to hormone therapy and the hormone therapy drug that will be recommended for you will depend on your menopausal status. These drugs are in pill form and you take them once a day. The most popular of these drugs, for pre-menopausal women, is Tamoxifen and, for post-menopausal women Femara or Arimidex. There is new evidence that suggests that taking Femara, after taking Tamoxifen for five years, increases survival rates. • Immunotherapy: There is a fourth modality of treatment on the horizon and it's called Immunotherapy. This involves getting your immune system to fight your cancer and there is, and will be, a lot of research being done in this area.
As women, especially American women, much of our femininity is centered on our breasts. No matter where you look, there are pictures, billboards, commercials, television shows, and movies with women with these beautiful breasts and ample cleavage. The thought of losing one or both breasts, to breast cancer, can be devastating for many of us. Sure, there's reconstruction, but will it ever really look the same again? Even if you have reconstruction, you'll never have sensation there again and, for many of us, that definitely affects our sexuality. I went through two separate mastectomies, for my breast cancer, despite the fact that I wanted them both done at the same time. Two different surgeons told me that wasn't necessary. They found out, later, that it was, as I had the same breast cancer in both breasts. Through these surgeries, I learned a few things about what to expect, and how to get up and running again, after a mastectomy for breast cancer. The first thing to realize is that, apart from the emotional aspect of such an operation, this is a simple surgery. The breast is composed, mostly, of fatty tissue and, of course, milk ducts and lobes. The removal of this breast tissue is way easier than operating on an organ, but carries much more emotional impact for most of us. Most surgeons will get as much of the breast tissue out as they can to help alleviate the chance of a recurrence of your breast cancer. You will typically wind up with a horizontal scar about four inches long. The scar may be red for quite a while but, ultimately, should fade to where you can hardly see it anymore. You want to be sure to take loose-fitting, button-down shirts (raiding your hubby's closet is helpful) with you, to the hospital, as you won't be able to raise your arms over your head for a while. You will also need a sports bra and I would highly recommend one that fastens in the front. They will put that on you after your surgery. Typically, you should be able to stay in the hospital for one night. If you're going to have lymph nodes removed, a small pillow, to slip under that arm, will help make you more comfortable. Check with your local American Cancer Society as they may have small pillows for you. An extra pillow to hold to your chest, if you need to cough, sneeze, or laugh, can help keep your incision from hurting. When you wake up, you will have a couple of drain tubes for each side you have done. These tubes are important as they allow the excess fluid, which your body will produce, to drain out. If you didn't have them, the fluid would have to be aspirated with a needle. The drains, even though they're no fun, are better than that. These drains will have to be emptied a couple of times a day and you will have to write down how much fluid you drain so the doctor will know when you've slowed down enough to remove them. You may not know where to put these drains under your clothing. I pinned mine up to the sports bra and that way, they didn't pull when I moved. When you get home, plan on having someone there to help you for the first few days. You won't be allowed to reach into your cabinets and definitely won't be able to clean house or pick up your children, if you have little ones. You'll be sent home with pain meds and definitely take them if you need them. Studies show that you will heal faster if you keep yourself out of pain, so don't be afraid to take them as prescribed. If you have a recliner, you might consider moving it into the bedroom as you won't be able to lie flat for a while. You'll need to sleep in a partial sitting position. If you don't have one, or don't have space for it in your bedroom, lots of pillows will work, too. That's what I used. Just be sure you have enough pillows to keep yourself comfortable propped up. If you would like someone who's been there before you to visit with, be sure to call your local American Cancer Society and ask for a Reach 2 Recovery volunteer. This is an American Cancer Society program where they try to match you with one of their volunteers who have as similar experience as you're facing. This woman will come visit you and will bring you all sorts of brochures and information on conventional treatment. She will also bring you a list of exercises you can start to do to regain your mobility and range of motion. This is VERY important. It hurts to stretch your arm up, after surgery, but if you haven't had reconstruction, and you don't start soon, you will lose that range of motion. I would recommend starting to gently, slowly reach your arm up … let your body be your guide … the day after your surgery. This is ONLY if you have not had reconstruction. If you have, let your plastic surgeon tell you when to start stretching. Push to where it hurts just a little, but do not push too far past that. Little by little, you'll find yourself able to stretch a little farther every couple of days. Most of all, allow yourself to heal emotionally, as well as physically. Some of us just can't look at that incision right away. That's OK. Take as much time as you need. I know I felt like some kind of freak with no breasts and, even six years later, I still do sometimes. But remind yourself that these scars are your battle scars. They do not make you less of a woman. They make you a warrior.
I always advocate self-care as the first step in preventing and treating health challenges. When it comes to breast health, the importance of self-care is a message I can't share often enough. It is great to see pink ribbons everywhere in October during National Breast Cancer Awareness Month! If I had my wish, every pink ribbon would carry an additional important message for women. That message would read "You can improve your breast health and reduce the risk of breast cancer right now with a few simple lifestyle changes." We may not be able to control where we live or our genetic risk factors - it's true. However, a growing body of research is showing us that women really can make a difference in their breast health through diet, exercise, and weight management. These simple steps can help optimize your body's hormonal balance and reduce the risk of developing breast cancer, and provide additional health, anti-aging, and disease-prevention benefits. We need to emphasize that everyone should be focusing on what we can control not what we can't. - We can evaluate our hormone levels with a saliva test. The best way for premenopausal and postmenopausal women to know if their bodies have an imbalance of estrogen, progesterone and testosterone is to do a saliva test. Saliva Testing is the most accurate and easy way to this. - We can use bio-identical hormones if we need hormone supplementation. Bio Identical means that the molecular structure of the hormones identically match the hormones made by our body as opposed to Pregnant Mare's Urine which is natural to horses not humans. - We can change our habits: reduce alcohol consumption and quit smoking. - We can manage our weight and exercise daily. Studies also show that maintaining a healthy, average weight is just as important in favorably influencing the estrogen/progesterone ratio. Regular exercise is equally important. On the other hand, obesity, high insulin levels, alcohol intake, smoking, oral contraceptives, hormones from meat and meat products, pesticides, and herbicides can swing this ratio in the wrong direction. - We can eat a balanced diet choosing Eat organic to avoid pesticides, herbicides, and estrogens in meat and dairy products. Include one to three servings of cruciferous vegetables like broccoli, bok choy, cauliflower, brussel sprouts, and cabbage in your diet each day. Studies show that Indole 3 Carbinol the active ingredient helps balance estrogen levels. - We Can supplement wisely with EFA's, essential fatty acids and use a fruit and vegetable concentrate if you do not eat 5 - 8 servings of fruits and vegetables daily. - We can do BSE's - breast self exams becoming more familiar with our own body - We can become better informed - read Dr. John Lee's "What Your Doctor May Not Tell You About Breast Cancer" as a start.
: The more you understand about any subject, the more interesting it becomes. As you read this article you'll find that the subject of cancer is certainly no exception. We hear it all the time? lose weight for your health. Few people however, realize the extent to which this is critical to their physical well-being and ultimately their life expectancy. In January 2003, the Journal of the American Medical Association featured a study finding that obesity appears to lessen life expectancy, especially among young adults. The researchers compared Body-Mass Index (BMI) to longevity and found a correlation between premature death and higher BMIs. For example, a 20-year-old white male, 5'10" weighing 288 pounds with a BMI of greater than 40 was estimated to lose 13 years of his life as a result of obesity. Jamie McManus, M. D., F. A.A. F.P. and author of "Your Personal Guide to Wellness" notes that while this study referenced extreme levels of obesity, there are still millions of overweight people in developed countries with a life expectancy rate that is three to five years less than their healthy-weight counterparts. She also estimates that there are 600,000 obesity related deaths each year in America. Just how does obesity shorten our lifespan? The answer to this question is complex, yet there is a clear link between obesity and the development of cancer. An extensive study conducted by the American Cancer Institute involving 750,000 people showed that obesity significantly increased the risk of cancer developing in the following organs: breast, colon, ovaries, uterus, pancreas, kidneys and gallbladder. Michael Thun, MD, vice-president of epidemiology and surveillance research for the American Cancer Society (ACS) says one reason obesity may raise cancer risk is because fat cells produce a form of estrogen called estradiol that promotes rapid division of cells, increasing chances of a random genetic error while cells are replicating, which can lead to cancer. In addition, fat centered around the abdomen may increase insulin and insulin-like growth factors in the blood, which may increase cancer risk. "Women who are obese after menopause have a 50% higher relative risk of breast cancer," notes Thun, "and obese men have a 40% higher relative risk of colon cancer?. Gallbladder and endometrial cancer risks are five times higher for obese individuals".There is evidence that cancer rates in developed countries are increasing at 5 to 15 times faster than developing countries. A major contributor to this alarming reality has proven to be diet. In populations where the diet consists mostly of fresh fruit and vegetables and whole grains ? in contrast to the typical Western diet of fatty meats, refined flours, oils and sugars ? the risk of cancer is much lower. The interaction of diet and the development of cancer is an active field of research and Dr David Heber, M. D., Ph. D. and author of "What Color is Your Diet", says "It appears that diet has its most significant effects after the cancer has already formed, acting to inhibit or stimulate the growth of that cancer". At the risk of oversimplifying a complex set of interactions, the typical Western diet that leads to obesity may actually act to stimulate the growth of cancer cells. It is never too late to improve your health through healthful eating and adopting a more health-giving lifestyle. Here are simple steps to follow which can make an immediate improvement to your health and vitality. The best time to learn about cancer is before you're in the thick of things. Wise readers will keep reading to earn some valuable cancer experience while it's still free. 1. Check your Body Mass Index (BMI) to determine if weight has become health risk. According to the Centers for Disease Control and Prevention, 60% of Americans are overweight, defined as having a BMI (a ratio of height to weight) over 25. Of those, nearly half (27%) qualify as obese, with a body mass index of 30 or more. In 1980, just 15% of Americans were considered obese. You can check your BMI at the website below. 2. Match your diet to your body's requirements. If you eat and drink more calories than your body requires you will put on weight. Learn to control calories and portion sizes, make recipes leaner, and eat infrequently from fast food restaurants. Also learn how to snack with healthful choices. 3. Color your diet with a large variety of colorful, cancer-fighting fruit and vegetables. There are seven different color ranges of both fruit and vegetables and by choosing between 5 to 9 daily serves from a wide range of fruit and vegetables, we are extending our consumption of cancer (and other disease) fighting nutrients. 4. Eat lean protein with every meal. Protein provides a powerful signal to the brain providing a longer sense of fullness. The right source of protein is essential to controlling your hunger with fewer calories and necessary to maintain your lean muscle mass. Choices of protein should be flavored soy shakes with fruit; the white meat of chicken and turkey, seafood such as shrimps, prawns scallops and lobster and ocean fish or vegetarians may prefer soy based meat substitutes. 5. Rev up your metabolism with activity. If you want to enjoy a lifetime of well-being, exercise is a key ingredient. Colleen Doyle, MS, RD, director of nutrition and physical activity for the American Cancer Society (ACS), says adults should do something for 30 minutes each day that takes as much effort as a brisk walk. Children should be active for an hour each day. We are more likely to develop habits around things we enjoy, so seek activities which you enjoy doing. It is also helpful to build physical activity into your daily routine: use the stairs instead of the escalator or lift at work, park your car in the parking bay furthest from the super marketing and don't use the remote control to change TV channels. 6. Get support to ensure you develop a healthful eating plan and reach your goal weight. Whilst a small percentage of people possess the discipline to lose weight, many obese people have developed strong thoughts and habits concerning the food they eat. In order to establish new habits, most people respond well to some form of consistent encouragement and coaching. A study, "Effects of Internet Behavioral Counseling on Weight Loss in Adults at Risk of Type 2 Diabetes" shows that participants who had the support of weight loss coaching lost more weight than those who didn't. The study concluded that the support of a weight loss coach can significantly improve weight loss results. Being overweight or obese has been identified next to smoking, as the most preventable major risk to developing cancer. Even small weight losses have been shown to have beneficial health effects. So it's never to late to start and you can never be too young or too old to be concerned about your health and do something about achieving a more healthy weight. Now might be a good time to write down the main points covered above. The act of putting it down on paper will help you remember what's important about cancer. In the meantime you can find out more by visiting the web site listed below. Keith Londrie is the creator of the treat-breast-cancer. info/ website that provides guidance and information to people about cancer. Visit today to answert all of your questions.
Some unique hardwood maple baskets woven by artisans in Ohio have been used to deliver hope-bringing millions of women potentially life-saving information about breast cancer. Through sales of these baskets, Horizon of Hope®, a partnership among The Longaberger Company, nearly 60,000 independent Longaberger home consultants and the American Cancer Society (ACS), has raised nearly $12 million for ACS since 1995 and reached an estimated 18 million women. In 2005, more than 200,000 Horizon of Hope baskets and thousands more related products were purchased. Every year, $2 from the sale of each basket and other campaign products go to ACS to fund research and education programs. "We truly are at our best when we gather together, and Horizon of Hope allows us to unite our sisterhood behind a cause that touches nearly all women in some way," said Tami Longaberger, chief executive officer of The Longaberger Company. "Thanks to the amazing efforts of our 60,000 home consultants, millions of women are benefiting from life saving breast cancer research and education." Many home consultants plan their own Horizon of Hope annual community events. Susan Kantor of Bartlett, Ill., is preparing for her tenth Horizon of Hope event, and nearly 1,000 guests are expected to attend. Kantor says attendance has continually grown every year since her team's first event, and this year cumulative donations will exceed the $300,000 mark. A committee of 20 women on her sales team plans all details of the event for months before it takes place, and many more team members are involved by inviting friends and helping out at the event. "Horizon of Hope gives me, my sales team, our customers and other friends a chance to do something wonderful for all women," says Kantor. "This is a cause that unites us because it has touched so many of us in some way." Theresa Razzante from Highland Heights, Ohio, also plans annual events with her team that she says have had immediate and positive results. This year is her team's eleventh event, with more than 500 expected to attend. "For months after our dinner one year, I had ladies share stories with me that they went for a mammogram-some their first one ever-because of our event," said Razzante. "I feel like I am making a difference in my community and in my families' and friends' lives." The Horizon of Hope Web site, horizonofhope, includes testimonials, information on funded programs and studies, and important prevention steps. The 2006 basket was designed as a jewelry box and features wood splints bent into the signature pink ribbon design, symbolic of breast cancer support. Offered in either Warm Brown or Whitewashed, the baskets are priced at $36 each or two for $64; a solid-wood lid in either color with a wood knob is available for $18, and a drawstring fabric liner is available for $14.
Significant progress in mammography technology continues to help physicians diagnose breast cancer in its earlier stages. When coupled with new treatment options, early diagnosis through mammography screening can significantly improve a woman's chances of survival. That's good news because in the United States more than 200,000 new cases of invasive breast cancer are diagnosed each year. Mammography screening is the single most effective method of early detection. That's why an annual mammogram is recommended for women over 40. A clinical breast examination by a health care professional should also be done on a regular basis. Additionally, women can take charge of their own breast health by understanding their personal risks of the disease, performing a breast self-exam every month and reporting any breast change promptly to their health care provider. Unfortunately, studies have indicated that a significant number of women over 40 years of age fail to get a mammogram, and of those who do, many never follow up with a second mammogram. Women cite a number of reasons for their nonparticipation, including lack of finances and lack of time. It is important that women know that there are resources available to help address these issues. For example, throughout the year, low-cost or free mammography screening is available to many women who are over 40 and underinsured or uninsured. Additionally, many mammography centers offer extended hours and some even provide child care for moms having mammograms. In an effort to encourage women to have an annual mammography screening, National Breast Cancer Awareness Month (NBCAM) sponsors recommend making every day National Mammography Day. Whether it means scheduling an appointment on a 40th birthday, or if it means reminding a friend to make an appointment, every step counts.
: We hear it all the time…lose weight for your health. Few people however, realize the extent to which this is critical to their physical well-being and ultimately their life expectancy. In January 2003, the Journal of the American Medical Association featured a study finding that obesity appears to lessen life expectancy, especially among young adults. The researchers compared Body-Mass Index (BMI) to longevity and found a correlation between premature death and higher BMIs. For example, a 20-year-old white male, 5’10” weighing 288 pounds with a BMI of greater than 40 was estimated to lose 13 years of his life as a result of obesity. Jamie McManus, M. D., F. A.A. F.P. and author of “Your Personal Guide to Wellness” notes that while this study referenced extreme levels of obesity, there are still millions of overweight people in developed countries with a life expectancy rate that is three to five years less than their healthy-weight counterparts. She also estimates that there are 600,000 obesity related deaths each year in America. Just how does obesity shorten our lifespan? The answer to this question is complex, yet there is a clear link between obesity and the development of cancer. An extensive study conducted by the American Cancer Institute involving 750,000 people showed that obesity significantly increased the risk of cancer developing in the following organs: breast, colon, ovaries, uterus, pancreas, kidneys and gallbladder. Michael Thun, MD, vice-president of epidemiology and surveillance research for the American Cancer Society (ACS) says one reason obesity may raise cancer risk is because fat cells produce a form of estrogen called estradiol that promotes rapid division of cells, increasing chances of a random genetic error while cells are replicating, which can lead to cancer. In addition, fat centered around the abdomen may increase insulin and insulin-like growth factors in the blood, which may increase cancer risk. "Women who are obese after menopause have a 50% higher relative risk of breast cancer," notes Thun, "and obese men have a 40% higher relative risk of colon cancer…. Gallbladder and endometrial cancer risks are five times higher for obese individuals”.There is evidence that cancer rates in developed countries are increasing at 5 to 15 times faster than developing countries. A major contributor to this alarming reality has proven to be diet. In populations where the diet consists mostly of fresh fruit and vegetables and whole grains – in contrast to the typical Western diet of fatty meats, refined flours, oils and sugars – the risk of cancer is much lower. The interaction of diet and the development of cancer is an active field of research and Dr David Heber, M. D., Ph. D. and author of “What Color is Your Diet”, says “It appears that diet has its most significant effects after the cancer has already formed, acting to inhibit or stimulate the growth of that cancer”. At the risk of oversimplifying a complex set of interactions, the typical Western diet that leads to obesity may actually act to stimulate the growth of cancer cells. It is never too late to improve your health through healthful eating and adopting a more health-giving lifestyle. Here are simple steps to follow which can make an immediate improvement to your health and vitality. 1. Check your Body Mass Index (BMI) to determine if weight has become health risk. According to the Centers for Disease Control and Prevention, 60% of Americans are overweight, defined as having a BMI (a ratio of height to weight) over 25. Of those, nearly half (27%) qualify as obese, with a body mass index of 30 or more. In 1980, just 15% of Americans were considered obese. You can check your BMI at the website below. 2. Match your diet to your body’s requirements. If you eat and drink more calories than your body requires you will put on weight.
Learn to control calories and portion sizes, make recipes leaner, and eat infrequently from fast food restaurants. Also learn how to snack with healthful choices. 3. Color your diet with a large variety of colorful, cancer-fighting fruit and vegetables. There are seven different color ranges of both fruit and vegetables and by choosing between 5 to 9 daily serves from a wide range of fruit and vegetables, we are extending our consumption of cancer (and other disease) fighting nutrients. 4. Eat lean protein with every meal. Protein provides a powerful signal to the brain providing a longer sense of fullness. The right source of protein is essential to controlling your hunger with fewer calories and necessary to maintain your lean muscle mass.
Choices of protein should be flavored soy shakes with fruit; the white meat of chicken and turkey, seafood such as shrimps, prawns scallops and lobster and ocean fish or vegetarians may prefer soy based meat substitutes. 5. Rev up your metabolism with activity. If you want to enjoy a lifetime of well-being, exercise is a key ingredient. Colleen Doyle, MS, RD, director of nutrition and physical activity for the American Cancer Society (ACS), says adults should do something for 30 minutes each day that takes as much effort as a brisk walk. Children should be active for an hour each day. We are more likely to develop habits around things we enjoy, so seek activities which you enjoy doing. It is also helpful to build physical activity into your daily routine: use the stairs instead of the escalator or lift at work, park your car in the parking bay furthest from the super marketing and don’t use the remote control to change TV channels.
6. Get support to ensure you develop a healthful eating plan and reach your goal weight. Whilst a small percentage of people possess the discipline to lose weight, many obese people have developed strong thoughts and habits concerning the food they eat. In order to establish new habits, most people respond well to some form of consistent encouragement and coaching. A study, “Effects of Internet Behavioral Counseling on Weight Loss in Adults at Risk of Type 2 Diabetes” shows that participants who had the support of weight loss coaching lost more weight than those who didn’t. The study concluded that the support of a weight loss coach can significantly improve weight loss results. Being overweight or obese has been identified next to smoking, as the most preventable major risk to developing cancer. Even small weight losses have been shown to have beneficial health effects. So it’s never to late to start and you can never be too young or too old to be concerned about your health and do something about achieving a more healthy weight.
Many of you will have heard of Paget's Disease, which is a serious bone disease, but many of you will not have heard of Paget's Disease of the breast, so I am hoping that the ladies out there reading this article will take notice of the content, because they could come in touch with this disease at some time in their life. What Is Paget's Disease Of The Breast? It is an eczema type change in the skin of the nipple, and most women that develop it, will have an underlying breast cancer. Paget's Disease occurs in about 1 or 2% of women that have breast cancer, it appears firstly as a scaly, red rash affecting the nipple and the areola. It can be very sore, may bleed and it will not go away. The disease can be difficult to diagnose, because it can be very similar to other skin problems like eczema or dermatitis, but this disease usually affects the nipple first then spreads to the areola, whereas the other skin problems usually start in the surrounding areas, first before spreading to the nipple. I have been asked to include the following in this article, it is taken from an actual case, where the person with the disease wanted this message passed on by you, to all the ladies in your life, Mothers, Daughters, Sisters, Aunts and Friends. "A lady developed a rash on her breast, similar to that of young mothers who are nursing. Because her mammogram had been clear, the doctor treated her with antibiotics for infections. After two treatments it continued to get worse, her doctor sent her for another mammogram, and this time it showed a mass. A biopsy found a fast growing malignancy. Chemotherapy was started in order to shrink the growth; then mastectomy; then a full round of Chemotherapy; followed by radiation treatment. After about 9 months of intense treatment, she was given a clean bill of health. She had one year of living each day to its fullest. Then the cancer returned to the liver area. She took four treatments and decided that she wanted quality of life, not the after effects of Chemotherapy. She had 5 great months, and she planned each detail of the final days. After just a few days of needing morphine, she slipped away saying she had done what God had sent her into the world to do." PLEASE be alert to any thing that is not normal. Her message is shown below: "Paget's Disease: This is a rare form of breast cancer, and is on the outside of the breast, on the nipple and areola. It appeared as a rash, which later became a lesion with a crusty outer edge. I would not have ever suspected it to be breast cancer, but it was. My nipple never seemed any different to me, but the rash bothered me, so I went to the doctor for that. Sometimes, it itched and was sore, but other than that it didn't bother me. It was just ugly and a nuisance, and could not be cleared up with all the creams prescribed by my doctor and dermatologist for the dermatitis on my eyes just prior to this outbreak. They seemed a little concerned. Mine started out as a single red pimple on the areola. One of the biggest problems with Paget's disease of the nipple is that the symptoms appear to be harmless. It is frequently thought to be a skin inflammation or infection, leading to unfortunate delays in detection and care. What are the symptoms? The symptoms include: A persistent redness, oozing, and crusting of your nipple causing it to itch and burn. (As I stated, mine did not itch or burn much, and had no oozing I was aware of, but it did have a crust along the outer edge on one side.) A sore on your nipple that will not heal. (Mine was on the areola area with a whitish thick looking area in center of nipple). Usually only one nipple is affected. How is it diagnosed? Your doctor will do a physical exam and should suggest having a mammogram of both breasts, done immediately. Even though the redness, oozing and crusting closely resembles dermatitis (inflammation of the skin), your doctor should suspect cancer if the sore is only on one breast. Your doctor should order a biopsy of your sore to confirm what is going on. This message should be taken seriously and passed on to as many of your relatives and friends as possible; it could save someone's life My breast cancer has spread and metastasized to my bones after receiving mega doses of chemotherapy, twenty eight treatments of radiation and taking Tamaxofin. If this had been diagnosed as breast cancer in the beginning, perhaps it would not have spread". TO ALL READERS: This is sad as women are not aware of Paget's disease. As we all know, early diagnosis is so important with all kinds of diseases, so if you are in any doubt about any medical problem, for goodness sake, make an appointment to see a Physician, soon as possible. If you would like to see more health information, that can help you, Please visit my web site.
There's encouraging news for women. Not only is it becoming easier to catch and treat breast cancer in its earliest stages, but new technologies are making the process of diagnosing the disease more comfortable for the patient-and more accurate as well. The National Cancer Institute recommends mammography screenings every one to two years for women over 40 and annually for women over 50. In addition, women at high risk of developing breast cancer (for example, women with a strong family history of breast cancer or who test positive for the BRCA breast cancer gene) are encouraged to begin annual mammography screenings even earlier-sometimes as young as 25-and should consult a physician. Benefits and risks • Early detection of small breast cancers greatly improves a woman's chances for successful treatment. If breast cancer is caught and treated while it is still confined to the breast ducts, the cure rate is close to 100 percent. • Clinical studies in the U. S., Sweden and the Netherlands have suggested that deaths from breast cancer could be cut by between 36 and 44 percent if screening mammography were performed annually on all women in their 40s. Digital mammography One of the most recent advances in breast cancer screening is digital mammography. Digital mammography uses essentially the same system as conventional mammography, but is equipped with a digital receptor and a computer instead of a film cassette. Digital mammography systems such as Siemens Medical Solutions' Mammomat® NovationDR enable faster and more accurate viewing of the dense tissue of the breast. Images are acquired digitally and displayed immediately on the system monitor. According to a recent study published in the New England Journal of Medicine, digital mammography was significantly better than conventional mammography at screening women in any of the following categories: • under age 50; • any age with very dense or extremely dense breasts; or • pre - or perimenopausal women of any age.
Tamoxifen, known in the trade as Nolvadex, is usually prescribed by specialists in breast cancer and is taken in pill form. A patient will stay on the drug for about five years. Often the woman's cancer will be tested to see if it is sensitive to the amount of oestrogen in the system. If the cancer is oestrogen sensitive, tamoxifen will be given. Because tamoxifen is such a weak estrogen, its estrogen signals don't stimulate very much cell growth. And because it has stolen the place away from more powerful estrogen, it blocks estrogen-stimulated cancer cell growth. In this way, tamoxifen acts like an "anti-estrogen." Tamoxifen may also take the place of natural estrogen in the receptors of healthy breast cells. In that way it holds down growth activity, and possibly stops abnormal growth and the development of a totally new breast cancer. By blocking natural estrogen from getting to the receptors, tamoxifen is helpful in reducing the risk of breast cancer in women at high risk who have never had breast cancer. It also can help women who have already had breast cancer in one breast by lowering the risk of a new breast cancer forming in the other breast. One study found that radiation plus tamoxifen was much better than tamoxifen alone at reducing the risk of breast cancer coming back after a lumpectomy in women with hormone-receptor-positive breast cancer. This was true even for women with very small cancers. For pre-menopausal women, tamoxifen is the best hormonal therapy. But tamoxifen is no longer the first choice for post-menopausal women. If you've been on tamoxifen for two to three years and now you're in menopause, your doctor may recommend that you switch to an aromatase inhibitor to finish your five years of hormonal therapy. However, you can still get a lot of benefit if you take tamoxifen for up to five years and then switch to an aromatase inhibitor. Tamoxifen was first used to fight breast cancer at the Christie Hospital in Manchester, England, in 1969. It has since proved its worth as means of stopping the spread or recurrence of the disease in women who have already been treated for it. But, it was noticed back in the early 1980s that some women who were receiving the drug for cancer in one breast did not develop any tumorous growth in the other. This prompted the suggestion that Tamoxifen might have another preventative role for those women who are at risk of getting breast cancer but have yet to develop any signs of the disease.
In 2006, more than 250,000 U. S. women will be diagnosed with breast cancer. This deadly disease will claim the lives of more than 40,000 friends, neighbors, mothers and daughters. These are staggering statistics. However, breast cancer death rates are going down. This decline is largely attributed to the benefits of annual mammograms that enable physicians to detect cancer at its earliest stages, and improved treatment programs that help patients better manage their cancer. Both digital and film-based mammography can identify breast disease in women who may have no obvious signs of breast cancer. Historically, mammograms have been conducted using medical X-ray film. Now, new digital imaging technologies are emerging that offer a complementary method for early detection of breast cancer. The arrival of more digital imaging options sometimes can cause some patients to "wait it out" until their health care provider installs digital imaging systems. But the advice from physicians appears to be overwhelming: Do not wait for the latest digital technology. One of the most critical aspects for a full recovery is early detection, and it is far better to have any kind of mammogram than to delay or skip a mammogram entirely. The decision on which imaging technology to use should be a secondary issue that patients can discuss with their physicians. "Digital technologies show great promise in helping to detect breast cancer in certain patients," said Dr. John M. Lewin, Diversified Radiology of Colorado, a leader in providing technologically advanced radiology imaging. "In fact, the Food and Drug Administration (FDA) is considering relaxing guidelines that may make it easier for manufacturers of digital mammography systems to bring new products to market faster." Should the FDA adopt revised guidelines, it is possible that health care providers and patients could have access to a broader range of new digital mammography products earlier-and perhaps at a lower cost-as more competition among manufacturers may drive down prices of these systems. One of the innovators of digital medical imaging systems is Eastman Kodak Company, which currently markets a digital mammography system for use in Europe, Latin America, Asia and other parts of the world. Kodak has applied to the FDA for approval to market this system in the U. S. and the company is conducting clinical trials of this system in the U. S. and Canada. "We applaud the FDA for examining ways to streamline the approval process for digital mammography products that may lead to increased adoption and improved access to these innovative systems," said Michael Marsh, vice president, Kodak's Health Group. Given the benefits and improvements in both digital and film mammogram technology, there is more reason now than ever before to encourage mothers, grandmothers, sisters and friends to get an annual mammogram. The American Cancer Society continues to recommend the importance of mammograms as a highly effective tool in the detection of breast cancer. What is critical is not the technology used to produce a mammogram, but ensuring that women age 40 and older have regular mammograms as part of maintaining a healthy lifestyle.
Many postmenopausal women are looking for alternatives to hormone therapy, especially in light of the recent Women's Health Initiative research findings concerning the risks of combined estrogen and progestin therapy. Of particular interest are phytoestrogens, which have been gaining popularity due to their "natural" status, alleged health claims, and availability in a wide range of foods and supplements. What are Phytoestrogens? Phytoestrogens are naturally occurring plant compounds that have some similarities to estradiol, the most potent naturally occurring estrogen. However, phytoestrogens tend to have weaker effects than most estrogens, are not stored in the body, and can be easily broken down and eliminated. Observational studies have found a lower prevalence of breast cancer, heart disease and hip fracture rates among people living in places like Southeast Asia, where diets are typically high in phytoestrogens. In North America, knowledge of these reported health effects has stimulated great interest in the health benefits of phytoestrogens. According to the Food and Drug Administration, the sale of soy foods, a major source of phytoestrogens, has increased dramatically in the past decade. Dietary Sources of Phytoestrogens Phytoestrogens consist of more than 20 compounds and can be found in more than 300 plants, such as herbs, grains and fruits. The three main classes of dietary phytoestrogens are isoflavones, lignans and coumestans: 1. Isoflavones (genistein, daidzein, glycitein and equol) are primarily found in soy beans and soy products, chickpeas and other legumes. 2. Lignans (enterolactone and enterodiol) are found in seeds (primarily flaxseed), cereal bran, legumes, and alcohol (beer and bourbon). 3. Coumestans (coumestrol) can be found in alfalfa and clover. Most food sources containing these compounds typically include more than one class of phytoestrogens. The Skeletal Effects of Phytoestrogens Much of the evidence concerning the potential role of phytoestrogens in bone health is based on animal studies. In fact, soybean protein, soy isoflavones, genistein, daidzein and coumestrol have all been shown to have a protective effect on bone in animals who had their ovaries surgically removed. In humans, however, the evidence is conflictingpared to Caucasian populations, documented hip fracture rates are lower in countries such as Hong Kong, China and Japan where dietary phytoestrogen intakes are high. Yet reports suggest that Japanese women have a greater risk of sustaining a vertebral fracture than Caucasian women. Several studies have explored the effects of soy isoflavones on bone health, but results have been mixed, ranging from a modest impact to no effect. Most of these studies have serious limitations, including their short duration and small sample size, making it difficult to fully evaluate the impact of these compounds on bone health. Ipriflavone Supplements Ipriflavone, a synthetic isoflavone, has shown some promise in its ability to conserve bone in postmenopausal women. Ipriflavone has also been shown to have a protective effect on bone density in pre-menopausal women taking gonadotropin-releasing hormone (GnRH), a treatment for endometriosis that triggers bone loss. However, a definitive three-year study of more than 400 postmenopausal women concluded that ipriflavone did not prevent bone loss. Additionally, the compound was linked to lymphocytopenia (a reduction in lymphocytes) in a significant number of study participants. Lymphocytes are a type of white blood cell that helps the body fight infection. Risks and Benefits Are Unclear Some studies suggest that, unlike estrogen, phytoestrogens do not appear to target breast or uterine tissue. This suggests that they may act more like SERMS (selective estrogen receptor modulators such as raloxifene and tamoxifen) than actual estrogens. However, in other studies high isoflavone levels have been linked to an increased risk of breast cancer. Clearly, additional research is needed to further evaluate the effects of phytoestrogens before judgments regarding their safety and usefulness can be made. Key Points Based on information available at this time, it is reasonable to make the following conclusions concerning phytoestrogens and bone health in postmenopausal women: 1. Moderate amounts of foods containing phytoestrogens can be safely included in the diet but do not expect it to help build bone. Keep to the basic rule - eat the least processed forms. 2. Due to a lack of evidence and concerns about safety, supplementation with synthetic isoflavones (ipriflavone) is in question. 3. Postmenopausal women are encouraged to view evidence concerning phytoestrogens and bone health as conflicting and incomplete. For women who are estrogen dominant increasing their phytoestrogen intake may not improve their bone position.
: Hunting for Genetic Mutations and Cancer The current paradigm in medical research holds that the cause of most cancers is a genetic mutation. For instance, according to the National Human Genome Research Institute (NHGRI), an institute at the NIH, "all cancers are based on genetic mutations in body cells." In fact, mutation hunting is big business. Just look at the NIH budget allocated to discoveries of genetic mutations, the number of biotech companies chasing genetic mutations, the magnitude of the licensing agreements between biotech and pharmaceutical companies aimed to utilize newly discovered genetic mutations, and the number of stories in the media on genetic mutations and their so-called "link" to disease. However, this huge effort and billions of dollars has produced few discoveries and little benefits to the public. The reason for this limited success is simple. The cause of cancer is not a genetic mutation. The story of the BRCA1 gene is a typical example of mutation hunting. The Mystery of BRCA1 Genes, in general, produce proteins, which are the building blocks of cells. The concentration of the protein is tightly regulated. A mutated gene produces an abnormal concentration of its protein, which may lead to disease. In 1994, Mark Skolnick, PhD, discovered the BRCA1 gene (BRCA1 is short for BReast CAncer 1). Following the discovery, scientists observed an abnormally low level of the BRCA1 protein in breast cancer tissues. The BRCA1 protein is a cell cycle suppressor, which means that the protein prevents cell replication. This observation created a lot of excitement. At the time, scientists believed that they were on the verge of finding the cause of breast cancer. The reasoning was that breast cancer patients must have a mutated BRCA1 gene, which would explain the decreased production of the protein, and the excessive replication of breast cancer cells in tumors. In the United States, 180,000 cases of breast cancer are diagnosed each year. However, the BRCA1 gene is mutated in less than 5% of these cases. In more than 95% of breast cancer patients the gene is not mutated. So here is the mystery. If the gene is not mutated in the great majority of the breast cancer patients, why are the tumors showing low levels of the BRCA1 protein? Today, this is one of the biggest mysteries in cancer research. The BRCA1 gene is not unique. Many normal (non-mutated) genes exhibit a mysterious abnormal (increased or decreased) production of proteins in cancer. Moreover, studies also report abnormal gene expression of normal genes in other diseases, such as atherosclerosis, obesity, osteoarthritis, type II diabetes, alopecia, type I diabetes, multiple sclerosis, asthma, lupus, thyroiditis, inflammatory bowel disease, rheumatoid arthritis, psoriasis, atopic dermatitis, and graft versus host disease. The Discovery A virus is a collection of genes. To replicate, some viruses settle in the nucleus of the host cell and use the cell machinery to replicate. What is the effect of a viral gene on the production of cellular proteins? Think of a gene as an assembly line of a protein. Like all assembly lines, the gene has two parts, a conveyor (the gene coding section), and a control panel (the gene promoter/enhancer). Imagine a cellular shop that assembles a product called BRCA1. One of the many buttons on the control panel is called N-box. Pressing the button increases production. However, only a small number of operators (called transcription factors), those who pass a special certification (called the p300 test), have permission to press this button. What happens when a virus opens a shop across the street from the cellular shop (called latent infection) to produce its viral products? The control panel in the viral shop also has an N-box button. To start production, the virus begins to hire away some of the certified operators. What is the effect of this "hiring away" on the number of available BRCA1 units? The number decreases. Moreover, the decrease becomes apparent even before the virus starts production (the "hiring away" is what creates the effect, not the viral proteins). The viral assembly line competes with the BRCA1 assembly line for the certified operators, and by hiring them away prevents the cellular shop from producing the optimum, or "healthy" number of BRCA1 units. The lower number of BRCA1 units leads to excessive cell replication and breast cancer. (See a more technical description in a recent paper published in the European Journal of Cancer.) The infection with the latent virus causes abnormal production of other genes, and as a result, the development of other chronic diseases. This sequence of events easily explains why people who suffer from obesity are also more likely to suffer from diabetes, cancer, and heart disease, and why a recent large scale study found that a low-fat diet does not protect against breast cancer. It also explains another surprising observation that male pattern baldness is associated with heart disease and prostate cancer. In general, this sequence of events easily explains the numerous observations indicating a co-existence or co-morbidity of some chronic diseases. This discovery was first described by Dr. Hanan Polansky in his book, Microcompetition with Foreign DNA and the Origin of Chronic Disease, published by The Center for the Biology of Chronic Disease. To summarize: the cause of cancer, and other chronic diseases, is not a genetic mutation, it's an infection with a latent virus. Reaction of the Scientific Community What is the scientific community saying about Dr. Polansky's discovery? Consider what the famous heart surgeon and "Living Legend," Michael E. DeBakey, said about the discovery, "The theory underlying the basic concept concerning the origin of chronic diseases presented by Dr. Polansky is most interesting, indeed fascinating … Perhaps a symposium could be held to provide a forum for further discussions and critiques of this fascinating theory." Elena N. Naumova, PhD, Associate Professor, Department of Family Medicine and Community Health, Tufts University School of Medicine, said, "Dr. Polansky's work compellingly demonstrates a framework that could bring together researchers from different fields. His proposed theory will work its magic by clarifying ambiguous definitions, identifying similarities and differences in various biological processes, and discovering new pathways … I believe that Dr. Polansky's book will catalyze the scientific learning process, promote interdisciplinary cross-fertilization, stimulate development of treatment strategies and drug discovery, and leave the reader inspired." Sivasubramanian Baskar, PhD, Senior Scientist from the National Cancer Institute, NIH, said, "At first, I wish to congratulate Dr. Hanan Polansky for his scientific bravery to take such a unique, novel approach to further stimulate our understanding of the origin and establishment of chronic diseases. The philosophy underscored is an excellent one ... The amazing correlation between theoretical predictions and observed in vivo effects seems to bring us a step closer to a deeper understanding of such complex biologic processes." Marc Pouliot, PhD, Assistant Professor, Department of Anatomy and Physiology, Faculty of Medicine, Universitй Laval, Canada, said, "The concept of microcompetition will change our approach in the study of chronic diseases and will furthermore give scientists a higher level of understanding in biology. Presentation of this concept undoubtedly provides a new set of opportunities for attacking chronic diseases … They lead the way to new approaches in chronic disease treatment." Howard A. Young, PhD, Section Head, Cellular and Molecular Immunology Section, Laboratory of Experimental Immunology, National Cancer Institute, NIH, said, "In summary, Dr. Polansky is to be applauded for his attempt to provide a unifying basis for chronic diseases. His theories are stimulating and offer a basis for experimental testing and possible treatment." Michael J. Gonzalez, PhD, Professor, Medical Sciences, University of Puerto Rico, said, "I know this book will profoundly impact medical research, drug discovery, as well as natural therapies. I also believe it will benefit the scientific community and society in general by providing further means of treatment for conditions in which only palliative care is available." You can find more reactions and the biographies the scientists reacting to Dr. Polansky's discovery on the publisher's (see link below). Hope for Cure and Protection The significance of Dr. Polansky's discovery cannot be overstated. For the first time, we can start to feel a little better about these diseases. With his discovery, pharmaceutical and biotech companies can now start to design medications that will target the cause of the disease rather than its symptoms, and therefore, cure the sick and protect the healthy from these deadly diseases.